I think I have an unusual approach to making music. I only have a laptop with Ableton Live and Absynth 4, so I do it all in Live. Often times what I'll do is create a patch in Absynth in standalone mode, and then save it and open up Live.
But I don't open the patch right away; I spend a lot of time making complex routings in Live like having track 1 go to send 1 which goes to track 2 which goes to send 2 etc... On all of these tracks and sends I set up different effects with different parameters, and have a final track which takes all of the previous tracks before it and goes to the master. On one project, I have 5 tracks and 5 sends going back and forth, all with reverbs with different parameters on them, and some grain delay on the final track, and it came amazingly close to sounding like a Steve Roach piece. I do all of this without ever listening to the initial patch, so when I'm done with routing stuff, I load up Absynth on track 1 and see what happens. Oftentimes, it works amazingly well. A patch with a short 1 second attack can take as long as 10 seconds for it to sound on the master channel through all of the effects. It sounds nothing like what the patch originally was, and is really just a smear of sound of all the reverb and delay that it goes through, but it sounds wonderful.
Ableton Live is really great. I actually had a <1 second sample the other day and turned it into a 5 minute piece through a complex routing. This way probably seems a little weird, but for me it produces great results.