Mike, you will enjoy the Greybeards questline a lot, if only to see the majesty of High Hrothgar. Looking down from there on the rest of Skyrim is pretty incredible. I imagine an avalanche of cheese wheels falling down from there would be awesome as well. Shouts are lots of fun.
I've had a blast playing the game. The world is immense, and I'm enjoying just exploring it. I just started the Mage College questline and am trying to follow that through to the end. It's easy to fill up with, and get distracted by side quests, of which I have way too many. Even with all that, and being level 32, I think I've only seen about a third of the game, if that.
I also find myself just looking around at some of the incredible sights. The city of Solitude perched on its rocky precipice. Walking across a stone bridge in a huge cavern with a waterfall trickling from a vaulted ceiling above and a dizzying drop below, light playing around the walls from torches or glowing lichen. Dragons sitting on the arches above a tomb before they see you and fly up to do battle. The twin moons rising above the mountains on a starry night. My Steam page(Yes, I'm Antdude there, too) is full of screenshots of my adventures so far.
The sound design is also incredible. Hearing a dragon crash down and roar the first time is quite the experience. Jeremy Soule has created probably his best musical score yet. It's suitably epic in battle(the Viking chorus shouting when you've defeated a dragon) and melodic when you're just exploring.
Many quests will send you into tombs and caves and you'll find yourself up against lots of unpleasant or undead creatures. There is one called Shroud Hearth Barrow, near Iverstead, that I really enjoyed battling through. Lots of enemies, booby traps and atmosphere to keep you company, with a nice payoff at the end.
If I haven't already sold it with all that puffery, this is definitely the Game of the Year for me. And with the editing tools soon to be released, the Elder Scrolls community will provide lots of new content for an already massive game.